At Vanderbilt there is a broad range of multi-disciplinary highly collaborative NIH-funded research programs in clinical, translational and basic science research in asthma and allergic diseases. The research programs fall into ten major focus areas covering respiratory epidemiology to basic eicosanoid biology and are summarized here [LINK TO RESEARCH PROGRAMS TAB]. The home of the clinical translational programs and faculty are within the Center for Asthma Research (https://www.vumc.org/aehr/welcome).

RESEARCH PROGRAMS

Allergic diseases, asthma and respiratory epidemiology

Programs in allergic diseases, asthma and respiratory epidemiology focus on risk factor identification, and translational studies to elucidate novel biologic pathways.

Faculty

Aspirin-exacerbated respiratory disease (AERD)

 

Eicosanoids and mediators in airway inflammation

 

Metabolomics

Metabolomics studies focus on using targeted and untargeted metabolomics in early life to elucidate the upstream pathways of asthma and allergic disease phenotypes.

 

Methodological considerations in asthma causal inference

As making valid causal inferences is challenging, these studies apply innovative methods and study designs to assess risk factor relationship with asthma and allergic disease outcomes.

 

Microbiome and asthma and allergic diseases

Human and laboratory studies focus on the role of the early life microbiome in acute respiratory morbidity and the development of chronic respiratory diseases, including asthma.

 

 

Obesity, glucose metabolism and asthma

 

Respiratory viral infections and their role in asthma and allergic diseases

Human clinical, translational and basic science studies of early life respiratory viral infections aim to decipher the role and mechanisms through which respiratory viruses contribute to acute and chronic respiratory diseases.

 

Sex differences in asthma and atopic diseases

  •  

Special populations: Cystic fibrosis and Down syndrome