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Gastroesophageal Reflux Disease, also known as GERD, is a digestive disorder that affects the lower esophageal sphincter (LES), which is the ring of muscle between the esophagus and stomach. GERD occurs when stomach acid flows back up into the esophagus causing irritation. The symptoms vary from patient to patient in both presence and severity, but common symptoms include:

  • A burning sensation in your chest, throat or mouth
  • Chest pain
  • Difficulty swallowing
  • Dry cough
  • Sore throat
  • Regurgitation of food
  • Sensation of a lump in your throat

Since GERD is a chronic disease, patients usually experience flares with obvious symptoms followed by periods of remission when they may not notice any symptoms at all. If left untreated, this can lead to serious esophageal complications.

Fortunately, there are several treatment options available for people living with GERD. If you have not had success with available treatment options, search the clinical trials listed below and talk with your doctor about the clinical trials you may be eligible for. Scientists and researchers are continually working to find ways to improve the quality of life for people living with GERD.

At Vanderbilt's GI Clinical Research Enterprise, we are dedicated to finding a solution that works for you.

Current Trials for GERD

We currently have no trials enrolling for GERD. Talk with your doctor about upcoming trials or other options available.