Major Research Areas of Division Faculty

Division researchers and clinicians are at the forefront of cancer research and treatment and provide the highest quality medical care available today. Following is a synopsis that reflects some of the major research areas of our faculty.

• Oncogenes and growth factor receptors in the pathogenesis of breast cancer; receptor tyrosine kinases as targets for antitumor therapy; molecular therapeutics in breast carcinoma.
• Molecular genetics of human solid tumors and the translation of these findings into clinical application
• Molecular fingerprinting of solid and hematologic malignancies using cDNA microarrays and MALDI-MS technologies.
• Cancer drug pharmacology.
• Study of leukemogenesis.
• Retroviral mediated gene transfer into hematopoietic stem cells; development of lentiviral vectors to achieve increased transduction of nondividing target cells.
• New drug development (Phase I and Phase II).
• Clinical translational research programs exist in multiple diseases including thoracic, breast, GI, GU, H&N and hematologic malignancies.