Continuous activation of cell surface receptors increases signaling that can promote oncogenic transformation. One receptor, EphA2, has been identified as a driver of lung cancer, but its interacting partners are not well characterized.
Breast-conserving surgery (BCS) plus radiotherapy is the standard-of-care for women diagnosed with early-stage breast cancer. For women over age 70, however, radiotherapy after BCS is controversial, and U.S.
Population-wide screening for genetic variants linked to hereditary breast and ovarian cancer may be cost effective in women between the ages of 20 and 35, according to a study published in JAMA Network Open.
Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox.
A minimally invasive procedure that combines ligation of the left atrial appendage (LAA) with hybrid epicardial-endocardial ablation is a feasible, safe and effective method of treating patients with longstanding atrial fibrillation (AF or AFib), according to a new Vanderbilt-led study.
From an analysis of 505,823 research subjects, Elizabeth Phillips, MD, and colleagues report in the American Journal of Human Genetics that individuals of European descent who carried a specific genetic variant were 47% more likely to have a self-reported penicillin allergy.
Leaders at Vanderbilt University Medical Center have announced that the Vanderbilt Memory and Alzheimer’s Center (VMAC), currently housed in the Department of Neurology, will become a freestanding institutional center.
Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19.
Excessive dietary salt is a major risk factor for hypertension and cardiovascular disease, but the mechanisms by which sodium elevates risk are not fully known.
After serving as interim chair since Jan.
