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One-two punch for cancer

March 05, 2020

Many cancer cells evade critical DNA surveillance and maintenance by increasing the export — by the Exportin-1 (XPO1) nucleo-cytoplasmic transport protein — of nearly all major tumor suppressor proteins from the nucleus.

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Potential new heartburn drug studied at VUMC

February 27, 2020

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

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Nashville VA dialysis unit named in Stone’s honor

February 13, 2020

On Feb. 11, the Nashville Veterans Affairs Medical Center (VAMC) dedicated its dialysis unit to William Stone, MD, a nephrologist and professor of Medicine at Vanderbilt University Medical Center, who retired from VUMC and VAMC in December after 50 years.

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Team tracks integrin’s role in lung function

February 06, 2020

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at Vanderbilt University Medical Center have discovered.

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HDL-cholesterol and breast cancer risk

January 31, 2020

Circulating lipids have been proposed to influence the risk of breast, colorectal and other common cancers, but results from conventional epidemiologic studies have been inconsistent.

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VUMC study to use artificial intelligence to explore suicide risk

January 23, 2020

With the help of a five-year, $2.7 million grant from the National Institute of Mental Health, researchers at Vanderbilt University Medical Center will use computational methods to shed light on suicidal ideation and its relationship to attempted suicide, predict suicidal ideation and suicide…

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