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The role of integrins in kidney “integrity”

January 13, 2022

Transmembrane receptors called integrins and proteins called laminins play important roles in the formation and function of tissues, including the ducts that collect urine from the filtering units of the kidneys. 

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Cell signaling targets in leukemia

December 09, 2021

Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15-20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little is known about how they affect cell signaling responses.

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