Professor, John A. Oates Chair In Clinical Research, Department of Medicine, Division of Infectious Diseases

Director of Personalized Immunology, Oates Institute for Experimental Therapeutics, VUMC

Professor, Pharmacology

Professor, Pathology, Immunology and Microbiology

Education

MD - University of Alberta
BMedSc - University of Alberta, Alberta, Canada

Clinical Interest

Research Keywords
HLA, T-cell immunology, immunogenomics, single cell, pharmacogenomics, drug hypersensitivity, SJS/TEN, Adverse drug reactions
Research Description

The Phillips lab has a research and clinical program in drug Hypersensitivity that specifically focuses on the tissue specificity, genetic basis and immunopathogenesis of severe T-cell mediated adverse drug reactions such as Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and drug reaction with eosiniophiia and systemic symptoms. Her lab studies the development of genetic, molecular and cellular signals to predict and prevent these severe life-threatening adverse drug reactions using novel single cell technologies and mass cytometry . Her impact has been national and international and she has forged collaborations with groups in Australia, Africa and Southeast Asia to guide in the implementation of scientific programs to study the expansive and genetically diverse drug hypersensitivity syndromes. This research program is paired with an outpatient clinical drug allergy service which occurs weekly at VASAP (2611 West End Ave).