Assistant Professor of Medicine

Research Description

Inflammation and stress signaling are critical determinants of cardiovascular and metabolic disease. Ultimately, these pathways converge in the nucleus to change chromatin structure and activate pathologic gene expression. A primary focus of the lab is to study how specific transcription factors and coregulators control these abnormal gene expression programs in cardiometabolic disease. In particular, the lab seeks to understand how chromatin-dependent signaling drives transcriptional programs that change cell state.  

Research Keywords

Cardiometabolic disease, vascular biology, inflammation, atherosclerosis, epigenetics, gene regulation, transcription, chromatin biology

Postgraduate Training


Internal Medicine, Brigham and Women’s Hospital, 2000-2001


Internal Medicine, Brigham and Women’s Hospital, 2001-2003


Cardiovascular Medicine, Brigham and Women’s Hospital, 2003-2006

Areas of Expertise

  • General Cardiology
  • Preventive Cardiology
  • Management of Hyperlipidemia
Previous Institution
Brigham and Women's Hospital/Harvard Medical School

Lab Address:
352 Preston Research Bldg., Nashville, TN
Topsfield, MA
Previous Role/Title
Staff Physician/Assistant Professor


MD - New York Medical College
Board and Certifications

Cardiovascular Disease 2006