Jonathan D. Brown, MD
Lab Address:
352 Preston Research Bldg., Nashville, TN
Assistant Professor of Medicine
Education
Relevant Links
Postgraduate Training
Internal Medicine, Brigham and Women’s Hospital, 2000-2001
Internal Medicine, Brigham and Women’s Hospital, 2001-2003
Cardiovascular Medicine, Brigham and Women’s Hospital, 2003-2006
Cardiovascular Disease 2006
Clinical Interest
Areas of Expertise
- ⇥
- General Cardiology ⇥
- Preventive Cardiology ⇥
- Management of Hyperlipidemia
Inflammation and stress signaling are critical determinants of cardiovascular and metabolic disease. Ultimately, these pathways converge in the nucleus to change chromatin structure and activate pathologic gene expression. A primary focus of the lab is to study how specific transcription factors and coregulators control these abnormal gene expression programs in cardiometabolic disease. In particular, the lab seeks to understand how chromatin-dependent signaling drives transcriptional programs that change cell state.