Lab Address:
352 Preston Research Bldg., Nashville, TN

Assistant Professor of Medicine

Hometown
Topsfield, MA
Previous Institution
Brigham and Women's Hospital/Harvard Medical School
Previous Role/Title
Staff Physician/Assistant Professor
Specialty
Medicine/Cardiology

Education

MD - New York Medical College

Postgraduate Training

Internship

Internal Medicine, Brigham and Women’s Hospital, 2000-2001

Residency

Internal Medicine, Brigham and Women’s Hospital, 2001-2003

Fellowship

Cardiovascular Medicine, Brigham and Women’s Hospital, 2003-2006

Board and Certifications

Cardiovascular Disease 2006

Clinical Interest

Areas of Expertise

  • General Cardiology
  • Preventive Cardiology
  • Management of Hyperlipidemia
Research Keywords
Cardiometabolic disease, vascular biology, inflammation, atherosclerosis, epigenetics, gene regulation, transcription, chromatin biology
Research Description

Inflammation and stress signaling are critical determinants of cardiovascular and metabolic disease. Ultimately, these pathways converge in the nucleus to change chromatin structure and activate pathologic gene expression. A primary focus of the lab is to study how specific transcription factors and coregulators control these abnormal gene expression programs in cardiometabolic disease. In particular, the lab seeks to understand how chromatin-dependent signaling drives transcriptional programs that change cell state.