Assistant Professor of Medicine
Division
Allergy, Pulmonary, and Critical Care Medicine

Assistant Professor of Medicine, Medicine

Professional Bio

Katherine Cahill, MD, is an Assistant Professor of Medicine in the Division of Allergy, Pulmonary, and Critical Care Medicine in the Department of Medicine at Vanderbilt University Medical Center.

She received her baccalaureate degree in biology from Pepperdine University, Malibu, California, and her MD degree from Robert Wood Johnson Medical School. Dr. Cahill completed her residency at Beth Israel Deaconess Medical Center in Boston, Massachusetts, and subsequently completed her fellowship training at Harvard Medical School. She is board certified in Internal Medicine and Allergy and Immunology.

Dr. Cahill’s research interests are focused on aspirin-exacerbated respiratory disease (AERD) and the treatment of severe asthma. She has published seminal work on the latter topic on the development of new therapies, including the use of tyrosine kinase inhibitors. As a clinical research fellow at Brigham and Women’s Hospital, Dr. Cahill was known for her exceptional bedside manner and astute concern for finding better treatment solutions for her allergy and asthma patients through translational research.

Dr. Cahill’s laboratory work has culminated in numerous conference presentations concerning successful experimental work studying the overproduction of the inflammatory prostaglandin and the relationship to the severity of disease manifestation in patients with AERD. She is a member of several prestigious organizations, including American Academy of Allergy, Asthma, and Immunology and the American Thoracic Society. She has given lectures throughout her career, published her findings in several well-recognized journals in the allergy field, and has demonstrated engagement and diligent work during her research immersion.

Dr. Cahill sees patients at the Vanderbilt Asthma, Sinus and Allergy Program. Her clinical interests include the evaluation and management of adult-onset asthma, aspirin-exacerbated respiratory disease (AERD), NSAID drug allergy, and eosinophilic diseases.

Education

MD - Robert Wood Johnson Medical School - 2007
Residency - Beth Israel Deaconess Medical Center - 2010
Fellowship - Clinical - Harvard Medical School - 2013
Fellowship - Clinical Research - Brigham and Women's Hospital - 2013

Publications

Laidlaw TM, Cahill KN, Cardet JC, Murphy K, Cui J, Dioneda B, Kothari P, Raby BA, Israel E, Boyce JA. A trial of type 12 purinergic (P2Y12) receptor inhibition with prasugrel identifies a potentially distinct endotype of patients with aspirin-exacerbated respiratory diseaseJ. Allergy Clin. Immunol [print-electronic]. 2018 Jun 6/8/2018; PMID: 29890239, PII: S0091-6749(18)30843-1, DOI: 10.1016/j.jaci.2018.06.001, ISSN: 1097-6825. 

Tuttle KL, Buchheit KM, Laidlaw TM, Cahill KNA retrospective analysis of mepolizumab in subjects with aspirin-exacerbated respiratory diseaseJ Allergy Clin Immunol Pract [print-electronic]. 2018 May; 6(3): 1045-7. PMID: 29501519, PMCID: PMC5997393, PII: S2213-2198(18)30118-1, DOI: 10.1016/j.jaip.2018.01.038, ISSN: 2213-2201. 

Schneider TR, Johns CB, Palumbo ML, Murphy KC, Cahill KN, Laidlaw TM. Dietary Fatty Acid Modification for the Treatment of Aspirin-Exacerbated Respiratory Disease: A Prospective Pilot TrialJ Allergy Clin Immunol Pract [print-electronic]. 2018 May; 6(3): 825-31. PMID: 29133219, PMCID: PMC5945343, PII: S2213-2198(17)30794-8, DOI: 10.1016/j.jaip.2017.10.011, ISSN: 2213-2201. 

Cahill KN, Boyce JA, Israel E. Novel Treatments for Airway Disease [letter]N. Engl. J. Med. 2017 Aug 8/10/2017; 377(6): 597. PMID: 28813135, PII: 10.1056/NEJMc1708004#SA5, DOI: 10.1056/NEJMc1708004, ISSN: 1533-4406. 

Cahill KN, Katz HR, Cui J, Lai J, Kazani S, Crosby-Thompson A, Garofalo D, Castro M, Jarjour N, DiMango E, Erzurum S, Trevor JL, Shenoy K, Chinchilli VM, Wechsler ME, Laidlaw TM, Boyce JA, Israel E. KIT Inhibition by Imatinib in Patients with Severe Refractory AsthmaN. Engl. J. Med. 2017 May 5/18/2017; 376(20): 1911-20. PMID: 28514613, PMCID: PMC5568669, DOI: 10.1056/NEJMoa1613125, ISSN: 1533-4406. 

Laidlaw TM, Cahill KNCurrent Knowledge and Management of Hypersensitivity to Aspirin and NSAIDsJ Allergy Clin Immunol Pract. 2017 May; 5(3): 537-45. PMID: 28483309, PII: S2213-2198(16)30559-1, DOI: 10.1016/j.jaip.2016.10.021, ISSN: 2213-2201. 

Cahill KN, Boyce JA. Aspirin-exacerbated respiratory disease: Mediators and mechanisms of a clinical disease [editorial]J. Allergy Clin. Immunol [print-electronic]. 2017 Mar; 139(3): 764-6. PMID: 27771324, PII: S0091-6749(16)31187-3, DOI: 10.1016/j.jaci.2016.09.025, ISSN: 1097-6825. 

Cahill KN, Johns CB, Cui J, Wickner P, Bates DW, Laidlaw TM, Beeler PE. Automated identification of an aspirin-exacerbated respiratory disease cohortJ. Allergy Clin. Immunol [print-electronic]. 2017 Mar; 139(3): 819-825.e6. PMID: 27567328, PMCID: PMC5266739, PII: S0091-6749(16)30700-X, DOI: 10.1016/j.jaci.2016.05.048, ISSN: 1097-6825. 

Cahill KN, Laidlaw TM. Pathogenesis of Aspirin-Induced Reactions in Aspirin-Exacerbated Respiratory DiseaseImmunol Allergy Clin North Am [print-electronic]. 2016 Nov; 36(4): 681-91. PMID: 27712763, PII: S0889-8561(16)30050-9, DOI: 10.1016/j.iac.2016.06.005, ISSN: 1557-8607. 

Shah NH, Schneider TR, DeFaria Yeh D, Cahill KN, Laidlaw TM. Eosinophilia-Associated Coronary Artery Vasospasm in Patients with Aspirin-Exacerbated Respiratory DiseaseJ Allergy Clin Immunol Pract [print-electronic]. 2016 Nov; 4(6): 1215-9. PMID: 27396680, PMCID: PMC5107156, PII: S2213-2198(16)30159-3, DOI: 10.1016/j.jaip.2016.04.028, ISSN: 2213-2201. 

Buchheit KM, Cahill KN, Katz HR, Murphy KC, Feng C, Lee-Sarwar K, Lai J, Bhattacharyya N, Israel E, Boyce JA, Laidlaw TM. Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory diseaseJ. Allergy Clin. Immunol [print-electronic]. 2016 May; 137(5): 1566-1576.e5. PMID: 26691435, PMCID: PMC4860132, PII: S0091-6749(15)01576-6, DOI: 10.1016/j.jaci.2015.10.020, ISSN: 1097-6825. 

Cahill KN, Raby BA, Zhou X, Guo F, Thibault D, Baccarelli A, Byun HM, Bhattacharyya N, Steinke JW, Boyce JA, Laidlaw TM. Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory DiseaseAm. J. Respir. Cell Mol. Biol. 2016 Jan; 54(1): 34-40. PMID: 26051534, PMCID: PMC4742927, DOI: 10.1165/rcmb.2014-0486OC, ISSN: 1535-4989. 

Stevens W, Buchheit K, Cahill KNAspirin-Exacerbated Diseases: Advances in Asthma with Nasal Polyposis, Urticaria, Angioedema, and AnaphylaxisCurr Allergy Asthma Rep. 2015 Dec; 15(12): 69. PMID: 26475526, PII: 10.1007/s11882-015-0569-2, DOI: 10.1007/s11882-015-0569-2, ISSN: 1534-6315.

Lee-Sarwar K, Johns C, Laidlaw TM, Cahill KNTolerance of daily low-dose aspirin does not preclude aspirin-exacerbated respiratory disease [letter]J Allergy Clin Immunol Pract [print-electronic]. 2015 May; 3(3): 449-51. PMID: 25634222, PMCID: PMC4426242, PII: S2213-2198(15)00012-4, DOI: 10.1016/j.jaip.2015.01.007, ISSN: 2213-2201. 

Cahill KN, Bensko JC, Boyce JA, Laidlaw TM. Prostaglandin D2: a dominant mediator of aspirin-exacerbated respiratory diseaseJ. Allergy Clin. Immunol [print-electronic]. 2015 Jan; 135(1): 245-52. PMID: 25218285, PMCID: PMC4289104, PII: S0091-6749(14)01030-6, DOI: 10.1016/j.jaci.2014.07.031, ISSN: 1097-6825. 

Cahill KN, Laidlaw TM. Aspirin exacerbated respiratory disease: the search for a biomarker [editorial]Ann. Allergy Asthma Immunol [print-electronic]. 2014 Nov; 113(5): 500-1. PMID: 25442693, PII: S1081-1206(14)00598-5, DOI: 10.1016/j.anai.2014.08.017, ISSN: 1534-4436. 

Hong DI, Bankova L, Cahill KN, Kyin T, Castells MC. Allergy to monoclonal antibodies: cutting-edge desensitization methods for cutting-edge therapiesExpert Rev Clin Immunol. 2012 Jan; 8(1): 43-52; quiz 53. PMID: 22149339, DOI: 10.1586/eci.11.75, ISSN: 1744-8409. 

Cahill KN, Kucharik CJ, Foley JA. Prairie restoration and carbon sequestration: difficulties quantifying C sources and sinks using a biometric approachEcol Appl. 2009 Dec; 19(8): 2185-201. PMID: 20014587, ISSN: 1051-0761. 

Hayhoe K, Cayan D, Field CB, Frumhoff PC, Maurer EP, Miller NL, Moser SC, Schneider SH, Cahill KN, Cleland EE, Dale L, Drapek R, Hanemann RM, Kalkstein LS, Lenihan J, Lunch CK, Neilson RP, Sheridan SC, Verville JH. Emissions pathways, climate change, and impacts on CaliforniaProc. Natl. Acad. Sci. U.S.A [print-electronic]. 2004 Aug 8/24/2004; 101(34): 12422-7. PMID: 15314227, PMCID: PMC514653, PII: 0404500101, DOI: 10.1073/pnas.0404500101, ISSN: 0027-8424.