Dr. Coate has had a longstanding interest in studying the metabolic aspects and molecular basis of diabetes. She obtained a doctoral degree in the laboratory of Dr. Alan D. Cherrington at Vanderbilt University where she found that a high-fat and high-sugar diet diminishes the ability of the liver to consume glucose and synthesize glycogen during conditions that mimic the fed state. This work highlighted the key regulatory role of the liver in mitigating postprandial hyperglycemia. She then pursued postdoctoral training in the joint laboratory of Drs. David Mangelsdorf and Steve Kliewer at UT Southwestern Medical Center. There, she defined the role of fibroblast growth factor 21 (FGF21) in the pancreas and discovered that FGF21 acts as a digestive enzyme secretagogue and protects pancreatic cells from protein-folding stress. After that, she joined the faculty at Samford University where she taught both undergraduate and graduate courses in nutrition and metabolism. In late 2019, she returned to research and moved to Vanderbilt University where she is a Research Instructor studying the human pancreas in type 1 and type 2 diabetes.
Katie Colbert Coate, PhD
Research Instructor in Medicine
PhD, Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee
MS, Nutrition, Auburn University, Auburn, Alabama
BS, Nutrition & Food Science, Auburn University, Auburn, Alabama