Professor of Medicine
Nephrology and Hypertension

Professor of Medicine, Division of Nephrology and Hypertension

Director of the Neilson Society, Department of Medicine

Professor of Surgery

Professional Bio

Mark P. de Caestecker, MBBS, PhD, is a Professor of Medicine in the Division of Nephrology and Hypertension within the Department of Medicine at Vanderbilt University Medical Center.

He trained as a physician-scientist at Cambridge University, University College London, and Manchester University, and completed his specialist training in General Internal Medicine and Nephrology at Manchester Royal Infirmary in England. In 1995 Dr. de Caestecker was awarded a Wellcome Trust Training Fellowship to work as a post-doctoral fellow with Dr. Anita Roberts at the NIH in Bethesda, Maryland. In 2000 he was recruited as junior faculty to the Department of Medicine at Vanderbilt and was promoted with tenure in 2009.

Dr. de Caestecker runs an NIH-funded lab-based research program in the Division of Nephrology. His lab is currently using genetic models in mice and patient derived IPS cells to evaluate effect of inherited mutations in the BMP type 2 receptor, BMPR2, on pulmonary vascular cell function, and using these approaches to evaluate the use of mutation-specific therapies to improve pulmonary vascular function in patients with heritable forms of pulmonary hypertension.


MA - Cambridge - 1980
MBBS - London - 1983
MRCP - UK - 1986
PhD - U of Manchester - 1994