Associate Professor of Medicine

Associate Professor of Medicine
Division
Clinical Pharmacology

Professional Bio

Meenakshi Madhur, MD, PhD, is an Associate Professor of Medicine in the Division of Pharmacology within the Department of Medicine at Vanderbilt University Medical Center. She earned her MD and PhD degrees in Molecular Physiology and Biological Physics from the University of Virginia, followed by an Internship and Fellowship at Duke University.

Dr. Madhur’s research focuses on hypertension, a leading cause of worldwide morbidity and mortality, leading to stroke, myocardial infarction, vascular disease, and chronic kidney disease. Emerging evidence from her laboratory and others indicates that hypertension is an inflammatory process in which T cells and T cell-derived cytokines play a central role. Despite this evidence, there are currently no treatments for hypertension that target the immune system. Dr. Madhur and her fellow researchers were the first to demonstrate a critical role for the pro-inflammatory cytokine, interleukin 17A (IL17A), in angiotensin II induced hypertension and vascular dysfunction.

In conjunction with Drs. David Harrison and Cheryl Laffer, and through a grant from Bristol-Myers Squibb, Dr. Madhur’s lab is performing a small pilot study in humans to determine the effect of Abatacept (which blocks T cell co-stimulation) on resistant hypertension and inflammatory parameters in humans.

Education

MD - Molecular Physiology and Biological Physics - University of Virginia - 2005
PhD - Molecular Physiology and Biological Physics - University of Virginia - 2005
Internship - and Residency Internal Medicine - Duke Univeristy - 2007
Fellowship - Cardiology - Duke University - 2012