Professor of Medicine

Thomas F. Frist Sr. Chair in Medicine, Vice Chair for Research, Department of Medicine

Research Description

The laboratory works on the basic role of integrins in epithelial cell biology. We utilize the kidney as a model system and perform biochemical techniques, cell biology and transgenic mice to understand the basic mechanisms whereby integrin-ECM interactions modify cell function. In addition, in collaboration with Dr. Charles Sanders, we perform structural functions on integrins utilizing NMR.

Research Keywords

Integrin biology, Kidney, Signal transduction, Branching morphogenesis,Kidney,Mouse

Office Address:
1161 21st Avenue South, Medical Center North, Room / Suite S-3223, Nashville, TN, TN 37232-2372
General Nephrology


Mmed - Medicine, University of Cape Town, South Africa
PhD, Cell Biology - University of Toronto, Toronto, Canada
MBBCh, Medicine - University of Witwatersrand, Johannesburg, South Africa