Office Address:
T-1217 MCN ((2650), Division of Allergy, Pulmonary & Critical Care Medicine, Medical Center North, Room / Suite T-1217, Nashville, TN 37232 (2650)

Rudy W. Jacobson Chair in Pulmonary Medicine, Professor of Medicine and Cell and Developmental Biology

Director, Division of Allergy, Pulmonary & Critical Care Medicine and the Center for Lung Research

Hometown
Birmingham, AL
Specialty
Lung Inflammation and Fibrosis

Education

MD - University of Alabama School of Medicine
BA - Vanderbilt University
Board and Certifications
Pulmonary and Critical Care

Clinical Interest

Interstitial lung disease, COPD, acute lung injury
Research Keywords
Lung, Inflammation, Fibrosis, COPD, Epithelial cells, Macrophages
Research Description

My laboratory investigates lung inflamamtion/injury, remodeling, fibrosis, and development of lung cancer. Lung inflammation is important for host defense functions but can contribute to tissue injury when the inflammation is excessive or dysregulated. By studying the NF-kB transcription pathway, we hope to better understand factors that control lung inflammation, injury, and host defense. We are also interested in the basic mechanisms that lead to normal lung repair or fibrosis following injury and mechanisms by which chronic inflammation alters the lung microenvironment in a pro-tumorigenic manner.