Professional Bio
Alain Gobert, PhD, is a Research Professor of Medicine in the Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University Medical Center. He has a particular interest in the study of host/pathogen interactions and has significant experience in the study of gastrointestinal inflammation and carcinogenesis.
After a PhD in Chemistry from the University of Bordeaux, France, Dr. Gobert completed postdoctoral training at the University of Maryland, Baltimore, where he conducted research on the role and the regulation of nitric oxide during infectious diseases of the gastrointestinal tract. His work uncovered the essential role of arginine metabolism in the control of Helicobacter pylori infection, inflammation, and gastric cancer. He was awarded a postdoctoral fellowship from The Pasteur Institute in Paris, France, to pursue his research on the inflammation associated with H. pylori.
Dr. Gobert began his independent research program at the French National Institute for Agricultural Research in 2003 where he and his group highlighted the molecular mechanisms by which NO regulates cellular attachment and toxin production by intestinal pathogenic bacteria. After a three-year sabbatical in the Division of Gastroenterology at Vanderbilt University Medical Center, Dr. Gobert joined the Center for Mucosal Inflammation and Cancer. His work aims to yield important insights into prevention and treatment of gastrointestinal inflammation and carcinogenesis through the regulation of the polyamine pathway, hypusination, and oxidation by dicarbonyl electrophiles.
Relevant Links
Publications
Education
PhD - Immunology - Universite Bordeaux I, 1999
Fellowship - Gastroenterology - University of Maryland, 2002
Fellowship - post doc - Universite Louis Pasteur (Strasbourg I), 2003
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307