Professional Bio
Alfredo J. Gamboa, MD, MSCI, is a Research Associate Professor of Medicine in the Division of Clinical Pharmacology within the Department of Medicine at Vanderbilt University Medical Center.
Dr. Gamboa's research focuses on the role of the autonomic nervous system in the regulation of blood pressure and metabolism. He is particularly interested in the impact of increased sympathetic activity on both endothelial dysfunction and insulin resistance in obesity associated hypertension. He and his fellow researchers are interested in understanding the role of the interactions between neural and local mechanisms that regulate blood pressure and glucose homeostasis. They run a complete autonomic laboratory that includes autonomic reflex testing, tilt table testing, microneurography (direct recording of sympathetic traffic), measurement of plasma catecholamines and metabolites, ganglionic blockade to induce transient autonomic failure, and estimation of norepinephrine spillover.
Dr. Gamboa and his fellow researchers also perform physiological and pharmacological tests using different techniques that include measurement of insulin sensitivity (insulin clamps with isotopes tracers), determination of peak oxygen consumption, measurement of cardiac output by the re-breathing method and the perfused forearm technique to assess endothelial function.
Publications
Education
MD - Universidad Peruana Cayetano Heredia, 1998
Fellowship - Clinical Pharmacology - Vanderbilt University, 2005
MSCI - Vanderbilt University, 2008
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307