Professional Bio
Dan Mark Roden, MD, is a Professor of Medicine in the Division of Genetic Medicine and Clinical Pharmacology within the Department of Medicine at Vanderbilt University Medical Center. He is also Professor Pharmacology and Biomedical Informatics, Director of the Oates Institute for Experimental Therapeutics, and Senior Vice President for Personalized Medicine.
Dr. Roden received his medical degree from McGill University. After completing residency training in internal medicine in Montreal, he came to Vanderbilt as a research fellow in the Division of Clinical Pharmacology and later as a fellow in cardiology. Since joining the Vanderbilt faculty in 1981, Dr. Roden has become internationally recognized for his studies of the mechanisms and treatment of abnormal heart rhythms and variability in drug response. One major interest has been pharmacogenomics, especially the role genetic variations play in adverse drug reactions such as drug-induced arrhythmias.
Dr. Roden directed the former Division of Clinical Pharmacology from 1992 to 2004 when he became founding director of the Oates Institute for Experimental Therapeutics. A fellow of the American Association for the Advancement of Science, he is author of more than 700 peer-reviewed scientific papers. He is a leader in VUMC's PREDICT project (Pharmacogenomic Resource for Enhanced Decisions in Care and Treatment), which since 2010 has applied genomic testing to drug prescribing in an effort to avoid adverse drug reactions.
He is principal investigator for the medical center's DNA databank, BioVU; co-principal investigator for the VUMC site of the NIH Electronic Medical Records and Genomics Network; and co-principal investigator for the Data and Research Center for the NIH's All of Us program.
The overall research theme in the Roden Lab is mechanisms underlying variability in response to drug therapy, with a particular focus on therapies used to treat cardiac arrhythmias. The individual projects focus on emerging models in molecular medicine and genetics, and incorporate the expertise of the laboratory in electrophysiologic methods.
Relevant Links
Publications
Education
MD - McGill University, 1974
Internship - Internal Medicine - Royal Victoria Hospital, 1975
Residency - Internal Medicine - McGill University, 1976
Residency - Royal Victoria Hospital, 1978
Fellowship - Clinical Pharmacology - Vanderbilt University, 1980
Fellowship - Cardiology - Vanderbilt University, 1981
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307