Professional Bio
Neeraj Joshi, PhD, is a Research Instructor in Medicine specializing in molecular genetics in the Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine at Vanderbilt University Medical Center. His career has focused on investigating DNA damage repair using multiple model systems, with demonstrated expertise in developing novel molecular assays with potential diagnostic applications and working individually and/or both at inter and intra-group levels.
Dr. Joshi earned his doctorate in regulatory biology from Cleveland State University, where he investigated mechanistic aspects of meiotic chromosome segregation. This resulted in 1. unraveling the role of genome architecture on meiotic DNA damage repair (DDR), 2. discovering a novel ultrasensitive DDR checkpoint system, and 3. developing a novel molecular assay "Homolog Pairing Capture." Collectively, these studies provided a new perspective on cellular DDR mechanisms and the first indirect involvement of the proteasome in the DDR process.
His current research at Vanderbilt is aimed at investigating receptor tyrosine kinase (RTK) signaling in cancer with an emphasis on epidermal growth factor receptor (EGFR) signaling, and mechanisms driving therapy resistance in colorectal cancer.
Education
MS - Biochemistry - University of Lucknow, 2001
PhD - Regulatory Biology - Cleveland State University, 2014
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307