Professional Bio
Nicholas Markham, MD, PhD, is an Assistant Professor of Medicine in the Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine at Vanderbilt University Medical Center. He is committed to improving gastrointestinal health as a physician and scientist.
In medical school, Dr. Markham was selected for the Canby Robinson Scholarship within the Vanderbilt Medical Scientist Training Program (MD/PhD). He received his PhD while working with the Reynolds lab in the Cancer Biology Department. His project opened new insight into molecular signaling via cellular adhesion proteins during development and tumorigenesis. During his graduate training, his publications related to understanding how cell-cell junction proteins contribute to development and disease by altering cytoskeletal and growth factor signaling pathways. Stemming from these projects, Dr. Markham became interested in C. difficile, because its toxins bind growth factor receptors and interfere with cytoskeletal dynamics. He stayed at VUMC to complete a gastroenterology fellowship and was a Harrison Society Scholar. He was selected for postdoctoral funding through the Division of Gastroenterology T32 training program. During fellowship, he published studies on growth factor signaling and gastrointestinal biology.
Dr. Markham has given oral presentations at Digestive Disease Week, the National Cancer Institute, and the American Association of Cancer Resesarch. He was awarded a VA Career Development Award and Vanderbilt Digestive Disease Research Center Pilot Project grant to study microbial toxins and their effect on receptor tyrosine kinases. He was selected to present his data on the interaction between the microbiome and colon cancer to the NCI Human Tumor Atlas Network.
Dr. Markham continues to pursue gastrointestinal biological research, with a focus is on enhancing our understanding of C. difficile infection and colon cancer.
Relevant Links
Education
MD - Vanderbilt University, 2014
PhD - Vanderbilt University, 2014
Internship - Vanderbilt University, 2015
Residency - Vanderbilt University, 2016
Fellowship - Vanderbilt University, 2020
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307