Professional Bio
Ravi Shah, MD, is the Gottlieb C. Friesinger II Endowed Chair in Cardiovascular Medicine and co-director of the Vanderbilt Diabetes Research Center. He serves as the Director of Clinical and Translational Cardiovascular Science in the Division of Cardiovascular Medicine, leads the NHLBI T32 in Cardiovascular Medicine at Vanderbilt University Medical Center (VUMC). He previously served as director of the Neilson Society, a Department of Medicine-wide society for mentorship of physicians and physician-scientists.
His laboratory studies mechanisms of cardiometabolic disease, diabetes, and human metabolism, with a focus on mechanisms of insulin resistance, fitness, and metabolic risk. He has actively studied mechanisms of tissue glucose disposal and insulin action in Indigenous Americans through active collaboration with NIDDK Phoenix Epidemiology Branch (U01DK123013) and the role of beta-cell-derived extracellular vesicles in diabetes (R01DK133847). He leads efforts in cardiometabolic phenotyping in the landmark NIDDK DCCT/EDIC study, where cardiopulmonary exercise testing, vascular reactivity, and echocardiography are being performed.
His prior work has also interrogated metabolic mechanisms linking nutrition, aging, and exercise to diabetes and diabetes-related complications (R01AG059729, R01HL136685, R01HL151841), including the use of organ-on-a-chip technologies and iPSC model systems, multi-omics, human physiologic studies, and genomics.
Dr. Shah is the Executive Committee Co-Chair of the Framingham Heart Study and works in multi-omics within the NHLBI TOPMed program (leading the VUMC TOPMed Laboratory Core with Drs. Alex Bick and Suman Das). His laboratory also participates in major NIH efforts, including the ECHO Study (U24-OD035523) and the Human Virome Project (U54).
Relevant Links
Publications
Education
MD - Harvard University, 2006
Internship - Internal Medicine - Massachusetts General Hospital, 2007
Residency - Internal Medicine - Massachusetts General Hospital, 2009
Fellowship - Cardiology - Massachusetts General Hospital, 2013
Fellowship - Heart Failure/Transplant - Massachusetts General Hospital, 2014
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307