Vineet Agrawal, MD, PhD, is an Assistant Professor of Medicine and physician-scientist with a clinical and research program devoted to understanding and treating heart failure with preserved ejection fraction (HFpEF), right ventricular dysfunction, and pulmonary vascular disease in heart failure.
Dr. Agrawal's work combines in vitro, in vivo animal, and in silico computational genomic methods to study etiologic and pathogenic drivers of cardiac and extracardiac remodeling in HFpEF. His basic science research program is currently investigating mechanisms by which alterations in TGF/BMP and natriuretic peptide signaling in the context of heart failure, specifically with emphasis on the role of these pathways upon regulating cardiomyocyte metabolism. His work also studies the mechanisms underlying pulmonary vascular remodeling in HFpEF animal models. Clinically, he complements his research interests through the direct care of patients with HFpEF, as well as through performing invasive diagnostic procedures in HFpEF patients such as right heart catheterization, endomyocardial biopsies, and invasive cardiopulmonary exercise testing. He is currently the director of the Invasive Cardiopulmonary Exercise Testing Laboratory at Vanderbilt University Medical Center.
Dr. Agrawal's work has been published in a number of journals such as Pulmonary Circulation, PNAS, Circulation Research, and Nature Communications. He is a recipient of numerous national awards and grants including the 2021 Pulmonary Hypertension Association Young Investigator Award, American Heart Association Career Development Award, NIH K08 Mentored Clinical Scientist Award, and Veterans Affairs Career Development Award. He also serves on a number of national committees including the American Thoracic Society Pulmonary Circulation Early Career Committee, AHA 3CPR Council Early Career Committee, and AHA 3CPR Communications Committee.