Nephrology and Hypertension

A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune ce

Four Vanderbilt University Medical Center faculty members have been elected this year to membership in the American Society for Clinical

Acute kidney injury (AKI) occurs in 12% of patients after noncardiac surgery and in up to 40% of patients post cardiac surgery. While there are not any reliable FDA-approved ways to prevent AKI post-surgery, Antonio Hernandez, MD, Edward Sherwood, PhD, MD, Mark de Castecker, MBBS, PhD, and colleagues are hoping to change this with their novel pretreatment strategy.

It’s time to revise the textbook entry for vasopressin production. For 100 years, it has been thought that vasopressin — a hormone that regulates water and blood pressure homeostasis — is only produced in the brain. Now, Vanderbilt University Medical Center investigators have discovered that vasopressin is also produced in the kidney. Their findings are featured on the cover of the Dec. 22, 2022, issue of JCI Insight.

“We are grateful for the over 7,000 kidney transplant patients that have entrusted us with their care since the start of the program 60 years ago,” said

Eliminating the race-based adjustment has several important clinical implications: it allows for more timely diagnosis, appropriate referral for treatment of early kidney disease, better disease management, earlier transplant listing, and more appropriate medication decisions for Black patients.

An in-depth analysis of published research studies supports removing race from the calculation of estimated glomerular filtration rate (eGFR) — an assessment of kidney function.

Tacrolimus — a commonly used immunosuppressive drug for lung transplant recipients — requires strict monitoring of concentrations because of variability in metabolism and adverse effects at high levels.