Professional Bio
Mark P. de Caestecker, MBBS, PhD, is a Professor of Medicine in the Division of Nephrology and Hypertension within the Department of Medicine at Vanderbilt University Medical Center.
He trained as a physician-scientist at Cambridge University, University College London, and Manchester University, and completed his specialist training in General Internal Medicine and Nephrology at Manchester Royal Infirmary in England. In 1995 Dr. de Caestecker was awarded a Wellcome Trust Training Fellowship to work as a post-doctoral fellow with Dr. Anita Roberts at the NIH in Bethesda, Maryland. In 2000 he was recruited as junior faculty to the Department of Medicine at Vanderbilt and was promoted with tenure in 2009.
Dr. de Caestecker runs an NIH-funded lab-based research program in the Division of Nephrology. His research focuses on the pre-clinical model development, and the development of novel therapeutics to improve outcomes after AKI. He currently hold four NIH awards to study 1.) Hdac8 as a therapeutic target for AKI (part of the Re-Building a Kidney Consortium); 2.) kidney targeted carbon monoxide (CO) prodrugs as an AKI therapy; and 3.) 3D molecular atlases of the human kidney (part of the HuBMAP and now KPMP consortia). He was a standing member of the RIBT NIH study section (2012-2018), ASN Grants Review Committee (2020-present), and Northwestern O'Brien Center Pilot Project Grants Reviewer (2019-present).
Dr. de Caestecker also has experience developing and coordinating educational resources at Vanderbilt University. He is the Director of the Aspire Program in Molecular Medicine, a two-year clinical enrichment program for 30 to 40 basic sciences graduate students (2012-present); Director of the Human Biology and Disease Course, and co-director of the Introduction to Clinical and Translational Research. He also developed and directed a number of training programs based at Vanderbilt including the Summer Research Training Program in Nephrology (2010-2020), the Mouse Kidney Injury Workshop (2010-present), and the Renal Translational Pathology Workshop (2019-present).
He was appointed Vice Chair for Faculty Development for the Department of Medicine (DOM) in 2019 and previously served as Director of the Nielson Society, a career development program that provides support, programming, and mentoring for 70 to 80 DOM junior faculty on the tenure track.
Relevant Links
Publications
Education
MA - University of Cambridge, 1980
MBBS - University of London, 1983
MRCP - University of Kentucky, 1986
PhD - University of Manchester, 1994
Contact
Email
Kimryn.Rathmell@Vumc.Org
Address
777 Preston Research Building
2220 Pierce Ave
Nashville, TN 37232-6307