Skip to main content
Home
Toggle menu

Give Now

  • For Patients
  • School Of Medicine
  • About
    • Leadership
    • Department Directory
    • News
    • Events
    • Annual Report
    • Nashville
  • Divisions
    • Allergy, Pulmonary and Critical Care Medicine
    • Cardiovascular Medicine
    • Clinical Pharmacology
    • Diabetes, Endocrinology and Metabolism
    • Epidemiology
    • Gastroenterology, Hepatology and Nutrition
    • General Internal Medicine and Public Health
    • Genetic Medicine
    • Geriatric Medicine
    • Hematology and Oncology
    • Infectious Diseases
    • Nephrology and Hypertension
    • Rheumatology and Immunology
  • Education
    • Overview
    • Internal Medicine Residency Program
    • Physician-Scientist Training Program
    • Internal Medicine-Pediatrics Residency Program
    • Fellowship Programs
    • EXCellence In TEaching Pathway
    • Physician-Scientist Doctoral Program
    • Medical Students
    • Alumni
    • Medicine Grand Rounds
  • Research
    • Overview
    • Clinical Trials
    • Publications
    • Research Centers and Labs
  • Faculty
    • Open Faculty Positions
    • Professional Development
  • Clinical Initiatives
    • Digital Health
    • Physician Builder Program
  • Diversity

User Detail

Patrick J Hu, MD, PhD

Division of Hematology Oncology

Associate Professor of Medicine

Director, Harrison Society

Patrick J Hu
Professional Bio
Patrick J. Hu, MD, PhD is the Director of the Harrison Society and Associate Professor of Medicine in the Division of Hematology and Oncology. In his role as director of the Harrison Society, Dr. Hu oversees the Physician-Scientist Training Program which utilizes the American Board of Internal Medicine (ABIM) Research Pathway to facilitate combined clinical and research training of individuals committed to careers in academic medicine. Dr. Hu is a clinically active oncologist with expertise in the management of pancreatic, colorectal, and anal cancers. His lab studies insulin and insulin-like growth factor signaling using the nematode Caenorhabditis elegans as a model organism. In C. elegans, the DAF-2 insulin receptor ortholog controls development, metabolism, and aging through a conserved PI 3-kinase/Akt cascade that regulates the FoxO transcription factor DAF-16. As FoxO transcription factors promote longevity in C. elegans and other species, including possibly humans, his research is focused on elucidating the mechanisms that govern both the regulation of FoxO activity as well as the FoxO outputs that are critical to its function in extending life span. The Hu group has pioneered the use of sensitized genetic screens to identify new modulators of C. elegans DAF-2 signaling. They have discovered several conserved genes that play previously unappreciated roles in DAF-16/FoxO regulation and function, and they are devising strategies to interrogate the function of orthologous genes in mammalian physiology and pathophysiology.
Relevant Links
VICC Faculty Directory
Publications
View Publications

Education

PhD - Biochemistry - New York University, 1995

MD - New York University, 1995

Residency - Internal Medicine - Johns Hopkins University, 1998

Fellowship - Medical Oncology - Harvard University, 2001

Fellowship - Genetics - Massachusetts General Hospital, 2005

Contact

Email 
Kimryn.Rathmell@Vumc.Org 
Address 
777 Preston Research Building 
2220 Pierce Ave 
Nashville, TN 37232-6307

Submitted by admin on Thu, 06/01/2023 - 04:28

Quick Links

  • Home
  • About
  • Divisions
  • Education
  • Research
  • Faculty
  • Diversity
  • Intranet

Contact Us

1161 21st Ave S
Nashville, TN 37232

(615) 322-5000

Support Our Work

Give Now

© Copyright 2023 Vanderbilt University Medical Center
Vanderbilt University Medical Center is committed to principles of equal opportunity and affirmative action. EOE/AA/Women/Minority/Vets/Disabled

sfy39587stp18