Vanderbilt University School of Medicine ranked 10th in the nation in total research grant support provided by the National Institutes of Health (NIH) in fiscal year 2023, according to figures compiled by the nonprofit Blue Ridge Institute for Medical Research.

More than 60 current clinical trials are using molecules called F2-isoprostanes (F2-IsoPs) as biomarkers of endogenous oxidative injury. Previous studies have shown that F2-IsoPs are increased in multiple oxidative stress-related diseases, including cardiovascular disease, neurodegeneration, diabetes, certain types of cancer and COVID-19.

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized adults worldwide.

Vanderbilt University Medical Center is working with scientists around the U.S. to launch the first phase 3, multicenter, placebo-controlled trial to determine the effect of immunomodulation on Long COVID (LC), also known as long-haul COVID or post-acute sequelae of COVID-19. The study is funded by the National Institutes of Health’s National Institute on Aging.

Ashley Spann, MD, MSACI, assistant professor of Medicine and Biomedical Informatics, is the inaugural recipient of the Harold Amos Medical Faculty Development Program Hepatology Award from the American Association for the Study of Liver Diseases (AASLD).

Sunil Kripalani, MD, MSc, Professor of Medicine (General Internal Medicine and Public Health), was honored for his service to translational scientists at Vanderbilt University Medical Center during the Vanderbilt Translational Research Forum.

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

Timothy Blackwell, MD, Rudy W. Jacobson Professor of Pulmonary Medicine and director of the Division of Allergy, Pulmonary and Critical Care Medicine, is leaving Vanderbilt University Medical Center to chair the Department of Internal Medicine at the University of Michigan. He assumes his new role on March 1.

A Vanderbilt study by Cardiovascular Medicine Drs. Hasan Siddiqi, Kelly Schlendorf and colleagues found no difference in one-year survival and other outcomes among heart transplant patients who received their new organs from from donation after circulatory death and donation after brain death.

Vanderbilt researchers, including Hematology and Oncology Drs. Justin Balko, Brian Lehmann and Vandana Abramson, have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.