International workgroup of geneticists issues CHEK2 guidelines
International workgroup issues additional guidance on how to manage patients who carry inherited CHEK2 gene mutations that put them at a higher risk for cancer.
Nancy Cox receives American Society of Human Genetics Leadership Award
Nancy Cox, PhD, the Mary Phillips Edmonds Gray Professor of Medicine at Vanderbilt University Medical Center and director of the Vanderbilt Genetics Institute, is the recipient of the 2023 ASHG Leadership Award from the American Society of Human Genetics.
Predicting gene expression may speed discovery: study
Eric Gamazon, PhD and colleagues at VUMC working with collaborators at the University of Cambridge have developed a method of “imputing,” or predicting gene expression in hard-to-access tissues like the brain from more accessible tissues, including whole blood.
Researchers clarify role of blood cell mutations in disease
More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease. Multiple DNA sequencing methods have been used to identify what is called “clonal hematopoiesis of indeterminate potential,” or CHIP, but it has been difficult to distinguish true mutations from artifacts.
VUMC researcher selected for Global Scholars Program
Vanderbilt researcher P. Brent Ferrell, MD, is leading one of five projects selected by the 2022 NIBR (Novartis Institutes for BioMedical Research) Global Scholars Program.
New ‘PoRT’ scale rebalances burden of initiating trust in science
A Vanderbilt University Medical Center-led team has developed a scale to measure trustworthiness in biomedical research among minority populations — a landmark tool for researchers to use to improve their own trustworthiness, and thus participation in research.
Research network yields significant findings related to obesity
In 2017, Vanderbilt University Medical Center was selected to be one of four U.S. medical centers in a Strategically Focused Research Network (SFRN) on Obesity funded by a four-year, $15 million award from the American Heart Association to study obesity and train future obesity-focused investigators.
Study sheds light on the development of inflammation, high blood pressure and resulting kidney damage
Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the
Translational Research Forum highlights range of studies
The 2022 Vanderbilt Translational Research Forum exemplified the range of studies conducted at Vanderbilt University Medical Center that