An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease.
Clinicians and scientists from around the world recently attended a symposium at Vanderbilt University Medical Center to honor the 75th birthday of Dan Roden, MD (Genetic Medicine and Clinical Pharmacology), a pioneer in personalized medicine and beloved colleague, mentor and friend.
Annet Kirabo, DVM, MSc, PhD, associate professor of Medicine (Genetic Medicine and Clinical Pharmacology), has been apppointed director of the Federation of Clinical Immunology Societies Center of Excellence (FCE) at VUMC. Rachel Bonami, PhD, assistant professor of Medicine (Rheumatology and Immunology), will serve as associate director of the Vanderbilt FCE.
Dr. Roden, Professor of Medicine, Pharmacology and Biomedical Informatics and Senior Vice President for Personalized Medicine, was awarded Vanderbilt’s most prestigious faculty honor for achievement in research.
A study led by researchers from Vanderbilt University Medical Center, including Department of Medicine Drs. Melinda Aldrich, Jacklyn Hellwege and Eric Gamazon has discovered genetic susceptibilities that may shed light on why people of African ancestry are disproportionately affected by lung cancer.
Michelle Southard-Smith, PhD, and colleagues, recently published a paper that details how single cell sequencing was used to identify how Sox10 mutations shift enteric neuron types by altering neuronal trajectories in early development of enteric nervous system development.
The largest genetic analysis of stuttering has demonstrated a clear genetic basis for the speech disorder, highlighting neurological pathways of risk. The study, published last week in the journal Nature Genetics by Dr. Piper Below (Genetic Medicine and Clinical Pharmacology) and colleagues, used data representing more than 1 million individuals who had their DNA analyzed by the company 23andMe Inc.
In a study that brings together genetics, gene expression and blood biomarkers, investigators have built a framework for exploring multiorgan cross talk in human health and disease.
Susan G. Komen has awarded $10.8 million in new research grants that will help propel innovative science and deliver hope to those facing breast cancer. The grant recipients include Department of Medicine faculty Drs. Tuya Pal (Genetic Medicine and Clinical Pharmacology) and Ben Ho Park (Hematology and Oncology).
An analysis of genetic sequencing data from more than 34,000 people over a 17-year period by researchers at VUMC, including by Alex Bick, MD, PhD (Genetic Medicine), has found that persistent cytopenia appears to be a critical step in the progression of CHIP to blood cancer.
