Medicine Grand Rounds Archive

Nov. 14, 2024

Presented by The Neilson Society

Speakers:

Tae Kon Kim, MD, PhD

Topic: "Optimizing immunotherapy in myeloid leukemia by modulating VISTA/PD-1H"

and 

Denis Mogilenko, PhD

Topic: "Role of Dendritic Cell Metabolism in Inflammation"

Dr. Tae Kon Kim (Hematology and Oncology) presented "Optimizing immunotherapy in myeloid leukemia by modulating VISTA/PD-1H." Key takeaways include:

• VISTA is highly expressed on AML blasts as well as immune cells
• VISTA blockade reverses immune evasion in AML
• VISTA blockade confers a synergistic anti-leukemia effect with PD-1 blockade

Dr. Denis Mogilenko (Rheumatology and Immunology) presented "Role of Dendritic Cell Metabolism in Inflammation." Key takeaways include:

• Dendritic cells are antigen presenting cells that integrate immune and metabolic signals to regulate inflammation
• Fatty acid metabolism of dendritic cells links obesity to chronic inflammation
• Glutamine metabolism of dendritic cells regulates antigen presentation

The recording of this Medicine Grand Rounds is not available for on-demand viewing.

Nov. 7, 2024

The Shull Lecture

Presented by the Division of Gastroenterology, Hepatology and Nutrition

Speaker:

Juan Pablo Arab, MD

Topic: "Insights into MetALD: Metabolic and Alcohol-associated Liver Disease"

Juan Pablo Arab, MD, FRCPC, is the Director of Alcohol Sciences at the Stravitz-Sanyal Institute of Liver Disease and Metabolic Health and Associate Professor of Medicine at the Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine.

Oct. 31, 2024

Presented by the Harrison Society

Speaker:

Jil Tardiff, MD, PhD

Topic: "Hypertrophic Cardiomyopathy in 2024: Linking Molecular Mechanisms to Patient Management - The Search For Novel Targets"

Jil Tardiff, MD, PhD,  is on faculty at the University of Arizona where she is a Professor of Biomedical Engineering, Medicine and Cellular and Molecular Medicine. She has been a practicing cardiologist for over 25 years and currently  holds the Steven M. Gootter Endowed Chair for the Prevention of Sudden Cardiac Death and is the Director of the Banner University Hospital – Tucson Hypertrophic Clinic.